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Overdose safety

Signs of an overdose and what to do. In an emergency, call 911.

ImportantSigns of an overdose

An overdose is an emergency. Call 911 right away if you see any of these signs. If you're not sure, treat it as an overdose.

Based on CDC. Not yet reviewed by a clinician.

Sources (3)
  1. 5 Things to Know About Naloxone
    Centers for Disease Control and Prevention, 2024-05-02
  2. Preventing an Opioid Overdose: Know the Signs. Save a Life.
    Centers for Disease Control and Prevention
  3. If You Think Someone Is Overdosing
    Centers for Disease Control and Prevention

What to do

Give naloxone if you have it, then call 911. Anyone can give naloxone, with or without medical training.

Stay with the person until help arrives. Most states have Good Samaritan laws that may protect you and the person overdosing from legal trouble when you call for help.

Based on CDC, FDA, and MedlinePlus. Not yet reviewed by a clinician.

Sources (5)
  1. 5 Things to Know About Naloxone
    Centers for Disease Control and Prevention, 2024-05-02
  2. Lifesaving Naloxone
    Centers for Disease Control and Prevention, 2025-06-11
  3. Information about Naloxone and Nalmefene
    U.S. Food and Drug Administration, 2024-08-08
  4. If You Think Someone Is Overdosing
    Centers for Disease Control and Prevention
  5. Naloxone Nasal Spray
    MedlinePlus, National Library of Medicine, 2026-09-15

ImportantNever mix 7-OH with alcohol, sedatives, or other opioids

7-OH acts like an opioid. Opioids and sedatives both slow your breathing. Taken together, they can cause a fatal overdose.

Based on NIDA and FDA. Not yet reviewed by a clinician.

Sources (2)
  1. Benzodiazepines and Opioids
    National Institute on Drug Abuse, 2022-11-07
  2. FDA and Kratom
    U.S. Food and Drug Administration

ImportantYour tolerance drops after you stop

After you stop, your body loses its tolerance. An amount you used to take can now cause an overdose. Most opioid overdose deaths happen in people who have just gone through withdrawal.

If you use again, carry naloxone and keep it at home.

Based on MedlinePlus and CDC. Not yet reviewed by a clinician.

Sources (2)
  1. Opiate and opioid withdrawal
    MedlinePlus, National Library of Medicine, 2026-05-15
  2. Lifesaving Naloxone
    Centers for Disease Control and Prevention, 2025-06-11

Getting naloxone

You don't need a prescription to buy naloxone nasal spray. It is sold over the counter in all 50 states. Many local health departments, community programs, and syringe services programs give it out for free or at low cost. Keep it where you and the people close to you can find it, and tell them where it is.

Based on FDA and CDC. Not yet reviewed by a clinician.

Sources (3)
  1. Information about Naloxone and Nalmefene
    U.S. Food and Drug Administration, 2024-08-08
  2. Lifesaving Naloxone
    Centers for Disease Control and Prevention, 2025-06-11
  3. 5 Things to Know About Naloxone
    Centers for Disease Control and Prevention, 2024-05-02

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